How quantitative differences in dendritic cell maturation can direct TH1/TH2-cell polarization
نویسنده
چکیده
The polarization of TH1 or TH2 responses by dendritic cells (DCs) requires distinct maturation conditions. Our data indicate that quantitative differences in DC maturation dictate a TH1 or TH2-cell polarization outcome. We discuss how chromatin remodeling at DC loci coding for pro-inflammatory vs. polarizing cytokines may explain differential TH-cell polarization.
منابع مشابه
بررسی اثر DNA آسیب دیده با داروی آلکیله کننده ملفالان بر میزان و کیفیت شاخص‌های بلوغ و جهت گیری فنوتیپ های ایمنی سلول‌های دندرتیک
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013